The dual genetic control of ornithine transcarbamylase synthesis in Escherichia coli K12
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چکیده
منابع مشابه
Roles of arginine and canavanine in the synthesis and repression of ornithine transcarbamylase by Escherichia coli.
Conditions were found under which the processes of repression and derepression of ornithine transcarbamylase were separated from the process of enzyme synthesis. After 10 min of arginine deprivation followed by the addition of 2 to 200 mug of l-arginine per ml, a number of strains of Escherichia coli exhibited a significant burst of ornithine transcarbamylase synthesis which lasted 3 to 4 min b...
متن کاملPath of Ornithine Synthesis in Escherichia Coli.
2 Leifer, E., Roth, L. J., and Hempelmann, L. H., Science, 108, 748 (1948). 3Hastings, A. B., Langham, W., Carter, R. E., and Roth, L. J., Nuclear Science Abstracts, 4, 806, No. 5372 (1950). 4Kornberg, H. L., and Davies, R. E., Intern. Congr. Biochem., Abstr. Commun., 2nd Congr., Paris, France, 1952, p. 144. 'f Scholander, P. F., Claff, C. L., Andrews, J. R., and Wallach, D. F., J. Gen. Physiol...
متن کاملGenetic analysis of the histidine operon in Escherichia coli K12.
I N Salmonella typhimurium a cluster of nine genes, behaving as a single operon (AMES and GARRY 1959) specify the enzymes which carry out the ten reactions involved in the biosynthesis of histidine; one of the nine enzymes is bifunctional (LOPER, GRABNAR, STAHL, HARTMAN and HARTMAN 1964). The histidine operon is contained in a linear segment of deoxyribonucleic acid (DNA) estimated by AMES, GOL...
متن کاملOrnithine Transcarbamylase Deficiency
Accumulation of ammonia in body tissues most commonly occurs in hepatic failure. However, it may also result from a specific deficiency of an enzyme of the urea cycle (Fig., 1). Severe hyperammonaemia has been reported with deficiencies of carbamyl phosphate synthetase (Freeman et al., 1964) and ornithine transcarbamylase (Russell et al., 1962; Levin and Russell, 1967). Some increase in blood a...
متن کاملAntepartum Ornithine Transcarbamylase Deficiency
Ornithine transcarbamylase deficiency (OTCD) is the most common type urea cycle enzyme deficiencies. This syndrome results from a deficiency of the mitochondrial enzyme ornithine transcarbamylase, which catalyzes the conversion of ornithine and carbamoyl phosphate to citrullin. Our case was a 28-year-old female diagnosed with OTCD following neurocognitive deficit during her first pregnancy. Alt...
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ژورنال
عنوان ژورنال: Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
سال: 1967
ISSN: 0027-5107
DOI: 10.1016/0027-5107(67)90083-8